Posted: 2016-05-11 in Press Releases
Nexvet to Host Symposium at American College of Veterinary Internal Medicine (ACVIM) Forum to Present Additional NV-01 Pivotal Data in Canine Pain and Clinical Data for NV-02 in Feline Pain
DUBLIN, Ireland, May 11, 2016 (GLOBE NEWSWIRE) -- Nexvet Biopharma (Nasdaq:NVET), a veterinary biologics developer, today announced it will host a symposium to present expanded pivotal safety and efficacy data for NV-01 (ranevetmab), a novel caninized anti-nerve growth factor (NGF) monoclonal antibody (mAb) under clinical investigation for the control of pain associated with osteoarthritis in dogs, and the latest clinical data for NV-02, the analogous felinized mAb for cats, at the ACVIM Forum in Denver, Colorado, on June 9th, 2016. In addition, Nexvet clinical collaborator Dr. Margaret Gruen of North Carolina State University’s Comparative Pain Research Program will present an extended clinical research abstract at ACVIM relating to Nexvet’s proof-of-concept efficacy study of NV-02 entitled “Feline Anti-Nerve Growth Factor Antibody Improves Mobility in Cats with Degenerative Joint Disease-Associated Pain” at 9AM UTC on June 11th.
The Company’s seminar on June 9th at 6:30AM - 8:30AM UTC will showcase the underlying biology of NGF, clinical study design of its chronic pain programs, as well as provide an update on ranevetmab’s pivotal safety and efficacy data in dogs with osteoarthritis. This study was announced to have met its primary efficacy endpoint (p ≤0.038) in November 2015. Professor Duncan Lascelles of North Carolina State University’s Comparative Pain Research Program, a leader in veterinary and comparative pain management, will be the featured speaker, providing the context for chronic pain in dogs and cats, including its measurement and unmet needs. Nexvet speakers will include: Dr Juergen Horn, Chief Product Development Officer, Dr. Colin Giles, Vice President, Clinical and Regulatory, and Dr. Jane Eagleson, Director of Clinical and Regulatory Affairs.
“As a company with programs in late-stage clinical development, we will increasingly utilize premier veterinary specialist conferences to engage with key opinion leaders and practicing veterinarians about biologics and Nexvet’s product candidates. Our market surveys have unequivocally demonstrated that a monthly subcutaneous injection for chronic pain indications in both dogs and cats is a very attractive concept and would be welcomed by veterinarians. mAbs targeting NGF are an entirely novel modality for veterinary pain management and are based on substantial validation from human clinical trials, validation we are the first to demonstrate from pivotal companion animal studies,” commented Dr. Mark Heffernan, Chief Executive Officer of Nexvet.
About Nexvet (www.nexvet.com)
Nexvet is a veterinary biologics developer focused on transforming the therapeutic market for companion animals, such as dogs and cats, by developing and commercializing novel, species-specific biologics. Nexvet’s proprietary PETization™ platform is designed to rapidly design monoclonal antibodies (mAbs) that are recognized as “self” or “native” by an animal’s immune system, a property Nexvet refers to as “100% species-specificity.” Nexvet’s product candidates also build upon the safety and efficacy data from clinically tested human therapies, thereby reducing clinical risk and development cost.
Nexvet is leveraging diverse global expertise and incentives to build a vertically integrated biopharmaceutical company, which conducts drug discovery in Australia, conducts clinical development in the United States and Europe and is growing its biomanufacturing capabilities in Ireland.
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